Date: Monday, 05/June/2023 (Program day 1 (pdf-file))
Registration I : Start: 8:00am
Welcome: 9:30am - 9:45am
Occurence
9:45am - 10:00am
Mycotoxin occurrence: a survey among major and minor winter cereals
Marco Gozzi1, Massimo Blandino2, Chiara Dall'Asta1, Renato Bruni1, Laura Righetti1,3,4
1: Department of Food and Drug, University of Parma, Italy; 2: Department of Agricultural Forest and Food Sciences, University of Turin, Italy; 3: Laboratory of Organic Chemistry, Wageningen University, The Netherlands; 4: Wageningen Food Safety Research, Wageningen University & Research, The Netherlands
10:00am - 10:15am
Putative tremorgenic mycotoxicosis in a dog – case report
Leon Hart1, Christina Rehagel1, Michael Kuhn2, Lukas Jozefowitz3, Esther Haßdenteufel3, Benedikt Cramer2, Ewald Usleber1
1: Chair of Dairy Sciences, Institute of Veterinary Food Science, Justus-Liebig-University, Giessen, Germany; 2: Institute of Food Chemistry, University of Münster, Münster, Germany; 3: Clinic for Small Animals, Department of Veterinary Clinical Sciences, Justus-Liebig-University, Giessen, Germany
Coffee break I: 10:15am - 11:00am
Food Safety I
11:00am - 11:15am
Fusarium Growth and Production of Toxins during Malting
Eva Maria Biehl, Sarah Schneidemann-Bostelmann, Ibrahim-Can Akpak, Michael Rychlik
Chair of Analytical Food Chemistry, Technical University of Munich (TUM), Maximus-von Imhof-Forum 2, 85354 Freising, Germany
11:15am - 11:30am
Mycotoxins as agricultural & livestock biosecurity threats: from maize seeds to raw milk contamination
Marta Sofia Carvalho Ferreira Malheiro Leite1,2,3, Andreia Freitas2,3, Jorge Barbosa3, Fernando Ramos1,3
1: University of Coimbra, Faculty of Pharmacy, Health Science Campus; 2: National Institute for Agricultural and Veterinary Research, I.P. (INIAV, I.P.); 3: Associated Laboratory for Green Chemistry (LAQV) of the Network of Chemistry and Technology (REQUIMTE)
11:30am - 11:45am
Investigations into the mycotoxin-producing capacity of moulds isolated from cheese
Daniela Schale1, Bettina Seeger1, Nadja Jeßberger1, Sophie Kittler1, Christina Rehagel2, Leon Hart2, Ewald Usleber2, Madeleine Plötz1
1: Institute of Food Quality and Food Safety, University of Veterinary Medicine Hannover; 2: Chair of Dairy Sciences, Institute of Veterinary Food Science, Justus-Liebig-University Giessen
11:45am - 12:00pm
Thermal stability of the mycotoxin citrinin
Lea Brückner, Benedikt Cramer, Hans-Ulrich Humpf
University of Muenster, Germany
Lunch I: 12:00am - 1:30pm
1:30pm - 1:45pm
Development and evaluation of sample preparation methods for mycotoxin analysis in plant-based milk alternatives by enzyme immunoassays
Christina Rehagel1, Ronal Maul2, Kim Lara Gützkow2, Ömer Akineden1, Ewal Usleber1
1: Chair of Dairy Sciences, Institute of Veterinary Food Science, Justus-Liebig-University, D-35390 Giessen, Germany; 2: Max Rubner-Institut Federal Research Institute of Nutrition and Food, Kiel, Germany
Toxicology I
1:45pm - 2:00pm
Combined toxicity of aflatoxin B1 and deoxynivalenol: roles of ribotoxicity and cytochrome P450 enzymes
Bernadette Willoquet, Gladys Mirey, Delphine Payros, Isabelle Oswald
Toxalim, Research center in Food Toxicology, Université de Toulouse, INRA, ENVT, INP-PURPAN, UPS, Toulouse, France
2:00pm - 2:15pm
Toxicity of enniatins A, A1, B, B1 and beauvericin on innovative in vitro Human cell models and their impacts on cellular gene expression.
France COULET, Monika COTON, Emmanuel COTON, Nolwenn HYMERY
Univ Brest, INRAE, Laboratoire Universitaire de Biodiversité et Écologie Microbienne, F-29280 Plouzané, France
2:15pm - 2:30pm
Computer-empowered digging of big data to tackle toxicity assessment and bioremediation of emerging mycotoxins - a 4-year long romance with fusaric acid
Lorenzo Pedroni, Chiara Dall'Asta, Gianni Galaverna, Luca Dellafiora
Department of Food and Drug, University of Parma, Italy
Coffee break II: 2:30pm - 3:00pm
Meeting of the Society for Mycotoxin Research: 3.00pm - 4:30pm
Activities: 5:00pm - 6:00pm
Barbecue: 6:30pm - open end
Date: Tuesday, 06/June/2023 (Program day 2 (pdf-file))
Registration II: 8:00am
Food Safety II
9:00am - 9:15am
Mycotoxin contamination in the Arab world: Highlighting the main knowledge gaps and discussing the current legislations
Mohamed Fathi Abdallah1, Muhammad Gado2, Doha Abdelsadek3, Fatma Zahran4, Nada N. El-Salhey5, Ohaila Mehrez6, Sara Abdel-Hay7, Sahar Mahrous8, Karl De Ruyck9, Elisabeth Varga10
1: Department of Veterinary Toxicology and Forensic Medicine, Assiut University, Assiut 71515, Egypt; 2: Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt; 3: Faculty of Pharmacy, Cairo University, Cairo 12613, Egypt; 4: Faculty of Pharmacy, Menoufia University, Menoufia 6131567, Egypt; 5: Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt; 6: Faculty of Pharmacy, Ain Shams University 11566, Cairo, Egypt; 7: Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt; 8: Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt; 9: Teagasc Food Research Centre, Ashtown, Dublin 15 D15 KN3K, Ireland; 10: Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria
9:15am - 9:30am
Mycotoxins in insects for food and feed
Ronald Maul1, Kim Lara Gützkow1, Nina Kröncke2, Johanna Ebmeyer3, Nadja Kampschulte4, Linda Böhmert3, Cindy Schöne5, Nils Helge Schebb4, Albert Braeuning3, Rainer Benning2
1: Max Rubner-Institut Federal Research Institute of Nutrition and Food, Germany; 2: University of Applied Sciences Bremerhaven, Germany; 3: German Federal Institute for Risk Assessment, Department Food Safety, Germany; 4: University of Wuppertal, Faculty of Mathematics and Natural Sciences, Chair of Food Chemistry, Germany; 5: German Federal Institute for Risk Assessment, Department Safety in the Food Chain, Germany
9:30am - 9:45am
T-2 and HT-2 toxins in milling oats and oat kernels
Jens Chr. Meyer
H. & J. Brüggen KG, Germany
9:45am - 10:00am
Cyclodextrins as potential mycotoxin binders: the summary of earlier and recent studies
Miklós Poór, Eszter Fliszár-Nyúl
Department of Pharmacology, Faculty of Pharmacy, University of Pécs, Pécs, Hungary
Coffee break III: 10:00am - 10:30am
Health / Exposure
10:30am - 10:45am
Ochratoxin A and Parkinson disease: is there a link?
Ariane Vettorazzi1,4, Maria Serrano1, Elba Beraza1, Maria Izco2, Amaya Azqueta1,4, Elena Gonzalez-Peñas3, Adela Lopez de Cerain1,4, Lydia Alvarez-Erviti2
1: Department of Pharmacology and Toxicology, MITOX Research Group, School of Pharmacy and Nutrition, University of Navarra, Pamplona, Spain; 2: Laboratory of Molecular Neurobiology, Center for Biomedical Research of La Rioja (CIBIR), Logroño, Spain; 3: Department of Pharmaceutical Technology and Chemistry, MITOX Research Group, School of Pharmacy and Nutrition, University of Navarra, Pamplona Spain; 4: IdiSNA, Navarra Institute for Health Research, Pamplona, Spain
10:45am - 11:00am
The epigenetic interplay of mycotoxins & Epstein Barr virus towards childhood cancer
Thanos Mouchtaris Michailidis1,2,4, Sarah De Saeger1,2,3, Rita Khoueiry4, Grace Akinyi Odongo4, Laura Corveleyn2,5, Maarten Dhaenens2,5, Zdenko Herceg4, Marthe De Boevre1,2
1: Ghent University, Ghent, Belgium; 2: CRIG, Cancer Research Institute Ghent, Ghent, Belgium; 3: Department of Biotechnology and Food Technology, Faculty of Science, University of Johannesburg, Doornfontein Campus, Gauteng, South Africa; 4: Epigenomics and Mechanisms Branch, International Agency for Research on Cancer/World Health Organization, Lyon, France; 5: Laboratory of Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Gent, Belgium
11:00am - 11:15am
Short-time exposure to the Fusarium mycotoxins deoxynivalenol and zearalenone in cows fed a diet inducing rumen acidosis
Lydia Kroon1, Ant Koopmans1, Antonio Gallo2, Janine Saltzmann3, Sven Dänicke3, Ermino Trevisi2, Regiane R Santos1
1: Schothorst Feed Research, P.O. Box 533, 8200 AM Lelystad, The Netherlands; 2: Department of Animal Science, Food and Nutrition (DIANA), Faculty of Agricultural, Food and Environmental Sciences, Università Cattolica del Sacro Cuore, 29122 Piacenza, Italy; 3: Institute of Animal Nutrition, Friedrich-Loeffler-Institute (FLI), Federal Research Institute for Animal Health, D-38116 Brunswick, Germany
11:15am - 11:30am
New insights on Citrinin exposure in German children and adults from a urine biomarker study
Gisela H. Degen1, Jörg Reinders1, Martin Kraft2, Yvonni Chovolou2, Wolfgang Völkel3, Felicia Gerull4, Jan G. Hengstler1, Hermann Fromme5
1: Leibniz Research Centre for Working Environment and Human Factors, Germany; 2: Landesamt für Natur, Umwelt und Verbraucherschutz NRW; D-45133 Essen, Germany; 3: Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit, D-80538 München; 4: Landeslabor Berlin-Brandenburg, Fachbereich IV-4, D-12489 Berlin; 5: Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin, D-80336 München
11:30am - 11:45am
Walls in Camouflage: Searching for Molds and Mycotoxins in Military Settings
Wiebke Derz1, Paul Elsinghorst1,2
1: Central Institute of the Bundeswehr Medical Service Munich, 85748 Garching, Germany; 2: Institute of Nutrition and Food Sciences, University of Bonn, 53121 Bonn, Germany
Lunch II: 11:45am - 1:45pm
Toxicology II
1:45pm - 2:00pm
Analysing epigenetic toxicity caused by multi-mycotoxin exposure using an intestinal and hepatic cell culture model
Yasmine Bader
University Ghent, Belgium
2:00pm - 2:15pm
New challenges in genotoxicity testing: the case of the Alternaria mycotoxins alternariol and altertoxin II
Francesco Crudo1, Chenyifan Hong1, Vanessa Partsch1, Giorgia Del Favero1, Luca Dellafiora2, Doris Marko1
1: Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Vienna, Austria; 2: Department of Food and Drug, University of Parma, Parma, Italy
2:15pm - 2:30pm
Does replication stress play a role in Ochratoxin A genotoxicity?
Christina Klotz, Julian Brode, Johannes Borchers, Angela Mally
University Würzburg, Germany
2:30pm - 2:45pm
Pitfalls and challenges when evaluating combinatory effects – a case study on zearalenone and isoflavones
Dino Grgic1,2, Barbara Novak3, Elisabeth Varga1, Doris Marko1
1: University of Vienna, Faculty of Chemistry, Department of Food Chemistry and Toxicology, Vienna, Austria; 2: University of Vienna, Doctoral School in Chemistry, Vienna, Austria; 3: DSM-Biomin Reserach Center, Tulln, Austria
2:45pm - 3:00pm
Alternariol-sulfates as neglected conjugation products with toxicological potential
Eszter Borsos1,2, Luca Dellafiora3, Chiara Dall'Asta3, Giorgia Del Favero1,4, Elisabeth Varga1, Doris Marko1
1: Department of Food Chemistry and Toxicology, University of Vienna, Vienna, Austria; 2: Doctoral School in Chemistry, University of Vienna, Vienna, Austria; 3: Department of Food and Drug, University of Parma, Parma, Italy; 4: Core Facility Multimodal Imaging, Faculty of Chemistry, University of Vienna, Vienna, Austria
Coffee break IV: 3:00pm - 3:30pm
Toxicology III
3:30pm - 3:45pm
New possibilities in mycotoxin research by functional intravital imaging
Ahmed Ghallab1,2, Reham Hassan1,2, Maiju Myllys1, Daniela González1, Abdellatif Seddek2, Andrea Gerdemann3, Michael Kuhn3, Benedikt Cramer3, Hans Ulrich Humpf3, Gisela H. Degen1, Jan G. Hengstler1
1: Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139 Dortmund, Germany; 2: Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, South Valley University, Qena 83523, Egypt; 3: Institute of Food Chemistry, Westfälische Wilhelms-Universität Münster, Corrensstr. 45, 48149 Münster, Germany
3:45pm - 4:00pm
Insights into the metabolism, kinetics and related toxicity of ochratoxin A in mice models
Michael Kuhn1, Reham Hassan2, Benedikt Cramer1, Ahmed Ghallab2, Gisela H. Degen2, Jan G. Hengstler2, Hans-Ulrich Humpf1
1: Institute of Food Chemistry, University of Muenster; 2: Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund
4:00pm - 4:15pm
Species differences of aflatoxin B1 metabolism in primary mouse, rat and human hepatocytes and in vivo in rodents
Andrea Gerdemann1, Benedikt Cramer1, Matthias Behrens1, Ahmed Ghallab2, Reham Hassan2, Gisela H. Degen2, Jan G. Hengstler2, Melanie Esselen1, Hans-Ulrich Humpf1
1: Institute of Food Chemistry, University of Münster, Münster, Germany; 2: Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany
Activities II: 4:30pm - 5:30pm
Conference Dinner: 6:30pm - open end
Date: Wednesday, 07/June/2023 (Program day 3 (pdf-file))
Registration III: 9:00am
Analysis / Fungi I
9:15am - 9:30am
LC-QToF-HRMS as an Effective Tool for Detecting of Co-Contamination of Mycotoxins and Transformation Products
Marcus Trentzsch, Stefan Weigel, Christoph Hutzler
German Federal Institute for Risk Assessment (BfR), Germany
9:30am - 9:45am
Acceleration of an HPLC-MS / MS multi-class method for the analysis of >1200 biotoxins, pesticides, and veterinary drugs
Lidija Kenjeric1, Michael Sulyok2, Rudolf Krska2,3, Kristyna Pavelicova4, Alexandra Malachova1
1: Austrian Competence Centre for Feed and Food Quality, Safety & Innovation, Austria; 2: 2. University of Natural Resources and Life Sciences Vienna (BOKU), Department of Agrobiotechnology (IFA-Tulln), Institute of Bioanalytics and Agro-Metabolomics, Konrad-Lorenz-Straße 20, 3430 Tulln an der Donau, Austria; 3: Institute for Global Food Security, School of Biological Sciences, Queens University Belfast, University Road, Belfast, BT7 1NN, Northern Ireland, United Kingdom; 4: Department of Chemistry and Biochemistry, Faculty of Forestry and Wood Technology, Mendel University in Brno, Zemedelska 1, Brno, Czech Republic
9:45am - 10:00am
IR spectroscopy combined with LC-MS/MS analysis for rapid mycotoxin screening
Stephan Freitag, Michael Sulyok, Rudolf Krska
Institute of Bioanalytics and Agro-Metabolomics, Department of Agrobiotechnology, IFA Tulln, University of Natural Resources and Life Sciences, Vienna
10:00am - 10:15am
Disarmed mycotoxins from Stachybotrys chartarum: insights into metabolism and biological activity of phenylspirodrimanes
Alica Fischle, Katharina Steinert, Viola Haupt, Felix Schimang, Hans-Ulrich Humpf, Svetlana A. Kalinina
Institute of Food Chemistry, University of Münster, Münster, Germany
10:15am - 10:30am
Effect of Deoxynivalenol on soil nitrification
Sven Korz, Katherine Munoz
RPTU, Institute for Environmental Sciences, Landau, Germany
Coffee break V: 10.30am - 11:00am
Fungi II
11:00am - 11:15am
Influence of the velvet complex on development, secondary metabolism, aggressiveness and defense of Penicillium expansum
Chrystian Zetina Serrano, Nadia Tahtah, Ophélie Rocher, Selma Snini, Yannick Lippi, Emilien L. Jamin, Isabelle P. Oswald, Olivier Puel, Sophie Lorber
INRAE, ToxAlim (Research Centre in Food Toxicology), Toulouse, France
11:15am - 11:30am
Linking distinct extrolite profiles to the different genetic populations within Penicillium roqueforti
Ewen Crequer1,2, Jean-Luc Jany1, Gwennina Cueff1, Jeanne Ropars2, Thibault Caron2, Jens Frisvad3, Johan Christiansen3, Antoine Branca2, Tatiana Giraud2, Emmanuel Coton1, Monika Coton1
1: Univ. Brest INRAE, Laboratoire Universitaire de Biodiversité et Ecologie Microbienne, F-29280 Plouzané, France; 2: Université Paris-Saclay, CNRS, AgroParisTech, Laboratoire Ecologie Systématique et Evolution, UMR 8079, France; 3: Department of Biotechnology and Biomedecine, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark
11:30am - 11:45am
Environmental influences on the production of Alternariol-Sulfate by Alternaria alternata
Adetoye Adeyemo, Markus Schmidt-Heydt
Max Rubner-Institute, Germany
Closing: 11:45am - 12:00am
Excursion (free, limited, registration required)
12:30pm
Bus departure for a visit Bruker Daltonics in Bremen (free, limited, registration required).
Free bus tour to the factory of Bruker Daltonics in Bremen. After the event no transfer back to Celle but to Bremen main station and airport.
2:30pm - 4:15pm
Visit of the Bruker Daltonics factory of mass spectrometers (free, limited, registration required)
Guided tour through the production factory and visit of the demo labs showing the latest developments of Bruker Daltonics.
For individual arrival: Meeting point in front of the main building, Fahrenheitstraße 4, 28359 Bremen
4:15pm
Snacks, drinks and discussions / Shuttle transfer to Bremen station and airport
Free drinks and snacks. Opportunity to discuss with experts from Bruker. Flights at 17:30 from Bremen to Munich or 19:10 to Frankfurt will be reached./-_-/res/04a38872-1e12-40b6-8c54-5deb07cee6d0/binary/files/04a38872-1e12-40b6-8c54-5deb07cee6d0/b1bc5631-bb75-4fb8-a002-3b1a2e688fc4
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